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Jeffreys enjoys being at the laboratory bench, and prepared his PhD thesis entitled " Studies on the mitochondria of cultured mammalian cells " as a postgraduate student at the Genetics Laboratory, University of Oxford.
After finishing his PhD, he moved to the University of Amsterdam, where he worked on mammalian genes as a research fellow.
He moved on to the University of Leicester in 1977, where he found an academically stimulating and helpful environment.
Working in Leicester he discovered a method of showing variations between individual's DNA in 1984, and invented and developed genetic fingerprinting.

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