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Fleming had been a private in the London Scottish Regiment of the Volunteer Force since 1900, and had been a member of the rifle club at the medical school.
The captain of the club, wishing to retain Fleming in the team suggested that he join the research department at St Mary's, where he became assistant bacteriologist to Sir Almroth Wright, a pioneer in vaccine therapy and immunology.
He gained a BSc with Gold Medal in 1908, and became a lecturer at St Mary's until 1914.
On 23 December 1915, Fleming married a trained nurse, Sarah Marion McElroy of Killala, County Mayo, Ireland.

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