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Alzheimer attended Aschaffenburg, Tübingen, Berlin, and Würzburg universities.
He received a medical degree at Würzburg University in 1887.
In the following year, he spent five months assisting mentally ill women, before he took an office in the city mental asylum in Frankfurt am Main: the Städtische Anstalt für Irre und Epileptische ( Asylum for Lunatics and Epileptics ).
Emil Sioli ( 1852 – 1922 ) was the dean of the asylum.
Another neurologist, Franz Nissl ( 1860 – 1919 ), began to work in the same asylum with Alzheimer, and they knew each other.
Much of Alzheimer's later work on brain pathology made use of Nissl's method of silver staining of the histological sections.
Alzheimer was the co-founder and co-publisher of the journal Zeitschrift für die gesamte Neurologie und Psychiatrie, though he never wrote a book that he could call his own.

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