Page "An Enquiry Concerning Human Understanding" Paragraph 38
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::" For here is the chief and most confounding objection to excessive skepticism, that no durable good can ever result from it ; while it remains in its full force and vigor.
He is immediately at a loss, and knows not what to answer ... a Pyrrhonian cannot expect, that his philosophy will have any constant influence on the mind: or if it had, that its influence would be beneficial to society.
On the contrary, he must acknowledge, if he will acknowledge anything, that all human life must perish, were his principles universally and steadily to prevail.
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