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While the Hellenistic Kingdoms ( the inheritors of Alexander the Great ) were fighting each other and the Galatians, Rome became the most powerful state in Europe and started to follow a policy of expansion to the east.
They invaded Macedon, Thrace, and the Dardanelles, and reaching Phrygia via Magnesia and Pisidia.
They cowed the Galatians and according to the treaty signed in Apamea in 188 BC, they gave the land of Pisidia which they had got from Antiochos III, to their ally the Pergamon Kingdom which dominated the region.
Attalos III, the last king of Pergamon, bequeathed his kingdom to Rome on his death in 133 BC Aristonikos who claimed Pergamon was defeated in 129, then Rome affected Anatolia with its well-developed, creative culture for centuries.

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