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Genomics has not only helped find targets for many antivirals, it has provided the basis for an entirely new type of drug, based on " antisense " molecules.
These are segments of DNA or RNA that are designed as complementary molecule to critical sections of viral genomes, and the binding of these antisense segments to these target sections blocks the operation of those genomes.
A phosphorothioate antisense drug named fomivirsen has been introduced, used to treat opportunistic eye infections in AIDS patients caused by cytomegalovirus, and other antisense antivirals are in development.
An antisense structural type that has proven especially valuable in research is morpholino antisense.

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