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Chewing areca nut alone has been linked to oral submucosal fibrosis.
According to Medline Plus, " Long-term use betel-areca preparations has been associated with oral submucosal fibrosis ( OSF ), pre-cancerous oral lesions and squamous cell carcinoma.
Acute effects of betel chewing include asthma exacerbation, hypertension, and tachycardia.
There may additionally be a higher risk of cancers of the liver, mouth, esophagus, stomach, prostate, cervix, and lung with regular betel use.
Other effects can include a possible effect on blood sugar levels, which may in turn increase the risk of developing type 2 diabetes.

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