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Constantius II, who succeeded Constantine, was an Arian sympathizer Following the abortive effort by Julian the Apostate to restore paganism in the empire, the emperor Valens — himself an Arian — renewed the persecution of Nicene hierarchs.
However, Valen's successor Theodosius I effectively wiped out Arianism once and for all among the elites of the Eastern Empire through a combination of imperial decree, persecution, and the calling of the Second Ecumenical Council in 381, which condemned Arius anew while reaffirming and expanding the Nicene Creed.
This generally ended the influence of Arianism among the non-Germanic peoples of the Roman Empire.

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