Page "Carcinoma" Paragraph 77

Carcinomas are usually staged with Roman numerals.

In most classifications, Stage I and Stage II carcinomas are confirmed when the tumor has been found to be small and / or to have spread to local structures only.

Stage III carcinomas typically have been found to have spread to regional lymph nodes, tissues, and / or organ structures, while Stage IV tumors have already metastasized through the blood to distant sites, tissues, or organs.