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In 1716, Elisabeth gave birth to the Infante Charles of Spain at the Real Alcázar of Madrid.
He was fourth in line to the Spanish throne, after three elder half-brothers: the Infante Luis, Prince of Asturias ( who ruled briefly as Louis I of Spain before dying in 1724 ), the Infante Felipe ( who died in 1719 ), and Ferdinand ( the future Ferdinand VI ).
Because the Duke Francesco of Parma and his heir were childless, Elisabeth sought the duchies of Parma and Piacenza for Charles.
She also sought for him the Grand Duchy of Tuscany, because Gian Gastone de ' Medici, Grand Duke of Tuscany ( 1671-1737 ) was also childless.
He was a distant cousin of hers, related via her great-grandmother Margherita de ' Medici, giving Charles a claim to the title through that lineage.

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