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Claire Weekes began her career as a research scientist, receiving her D Sc in 1930 from the University of Sydney ; she was the first woman to attain that degree from the university.
Working under Prof. Launcelot Harrison, she conducted research on reproduction and placentation in viviparous ( live-bearing ) lizards from 1925 – 1934 ; part of this period ( 1929 – 1931 ) was spent in England in the lab of J. P. Hill.
Weekes ' work led to eight published papers, including a major summary published in 1935 in the Proceedings of the Zoological Society of London.
Weekes ' work provided the basis an understanding of reptile placentation that lasted for nearly 50 years.
More recent work has continued to build on the empirical and conceptual framework that she established.

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