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Constantine Doukas was the son of Andronikos Doukas, a Paphlagonian nobleman who may have served as governor of the theme of Moesia.
Addicted to endless debates about philosophy and theology, Constantine gained influence after he married, as his second wife, Eudokia Makrembolitissa, the niece of Patriarch Michael Keroularios.
In 1057, Constantine supported the usurpation of Isaac I Komnenos, but gradually sided with the court bureaucracy against the new emperor's reforms.
In spite of this tacit opposition, Constantine was chosen as successor by the ailing Isaac in November, 1059, under the influence of Michael Psellos.
Isaac abdicated and on November 24, 1059, Constantine X Doukas was crowned emperor.

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