Page "Cramp" Paragraph 15

Statins sometimes cause myalgia and cramps among other possible side effects.

Additional factors, which increase the probability for these side effects, are physical exercise, age, female gender, history of cramps, and hypothyroidism.

Up to 80 % of athletes using statins suffer significant adverse muscular effects, including cramps ; the rate appears to be approximately 10 – 25 % in a typical statin-using population.

In some cases, adverse effects disappear after switching to a different statin ; however, they should not be ignored if they persist, as they can, in rare cases, develop into more serious problems.

Coenzyme Q10 supplementation can be helpful to avoid some statin-related adverse effects, but currently there is not enough evidence to prove the effectiveness in avoiding myopathy or myalgia.