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Most of the plants in this family are annual vines but there are also woody lianas, thorny shrubs, and trees ( Dendrosicyos ).
Many species have large, yellow or white flowers.
The stems are hairy and pentangular.
Tendrils are present at 90 ° to the leaf petioles at nodes.
Leaves are exstipulate alternate simple palmately lobed or palmately compound.
The flowers are unisexual, with male and female flowers on different plants ( dioecious ) or on the same plant ( monoecious ).
The female flowers have inferior ovaries.
The fruit is often a kind of modified berry called a pepo.

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