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Similar to other psychedelic drugs, there are relatively few physical side effects associated with DMT acute exposure.
When inhaled, its vapor has been described as " very harsh.
" According to a " Dose-response study of N, N-dimethyltryptamine in humans " by Rick Strassman, " Dimethyltryptamine dose slightly elevated blood pressure, heart rate, pupil diameter, and rectal temperature, in addition to elevating blood concentrations of beta-endorphin, corticotropin, cortisol, and prolactin.
Growth hormone blood levels rose equally in response to all doses of DMT, and melatonin levels were unaffected.

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