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Following back-to-back second round losses in Tokyo and Beijing, Safina lost the No. 1 rank to Serena Williams.
She regained it two weeks later on October 26.
At the WTA Tour Championships, she had a chance to end the season as No. 1 for the first time in her career, but retired due to a back injury in her first round robin match, which she claimed had been bothering her for three months.

2.143 seconds.