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In June 1999, Rite Aid entered into a ten-year strategic relationship with drugstore. com which allowed drugstore. com customers to pick up prescriptions at Rite Aid stores, and enabled drugstore. com to sell Rite Aid products, as well as vitamins from retailer General Nutrition Center ( GNC ).

On September 3, 2008, drugstore. com amended and restated both the main agreement and the pharmacy supply and services agreement dated June 17, 1999 between Rite Aid and drugstore. com.

Through those agreements with Rite Aid, drugstore. com had access to Rite Aid customers through the RiteAid. com website and the Rite Aid online store, which was powered by the drugstore. com website.

Drugstore. com ended a sourcing deal with Amazon. com in 2005.

In addition to the Drugstore. com website, the company also maintains storefronts at: Beauty. com, sexualwellbeing. com, AtHisBest. com, allergysuperstore. com, TheNaturalStore. com, and VisionDirect. com.