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AstraZeneca claims that esomeprazole provides improved efficacy, in terms of stomach acid control, over the R enantiomer of omeprazole.
Many noted health professionals including Dr. Otis Brawley ( author of " How We Do Harm: A Doctor Breaks Ranks About Being Sick In America ", and currently ( as of August 2012 ) both chief medical officer and executive vice president of the American Cancer Society ) have expressed the view that this improvement in efficacy is due to the dose of esomeprazole recommended for therapy rather than any inherent superiority of esomeprazole.
And in his 2003 address to the American Medical Association, Thomas Sully, then director of the Center for Medicare & Medicaid Services told his audience " You should be embarrassed if you prescribe Nexium because it increases costs with no medical benefits ….
The fact is Nexium is Prilosec … it is the same drug.
It is a mirror compound.

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