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The efficacy of melodic intonation therapy has been proven by studies that show that MIT can result in greater recovery when compared to non-intonation therapy.
FMRI studies have proven that melodic intonation therapy uses both sides of the brain to recover lost function, as opposed to traditional therapies that utilize only the left hemisphere.
Furthermore, it has been seen that, in MIT, individuals with small lesions in the left hemisphere seem to recover by activation of the left hemisphere perilesional cortex, while, in individuals with larger left-hemisphere lesions, there is a recruitment of the use of language-capable regions in the right hemisphere.

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