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Asimov " was sent a suggested outline " that mirrored the movie Innerspace and " involved two vessels in the bloodstream, one American and one Soviet, and what followed was a kind of submicroscopic version of World War III ".
Asimov was against such an approach.
Following a dispute between publishers, the original commissioners of the novel approached Philip Farmer, who " wrote a novel and sent the manuscript " that was rejected despite " stick tightly to the outline was sent to Asimov ".
" It dealt with World War III in the bloodstream, and it was full of action and excitement ".
Although Asimov urged the publisher to accept Farmer's manuscript, it was insisted that Asimov write the novel.
So, Asimov eventually wrote the book in his own way ( completely different in plot from what had written ), which was eventually published by Doubleday in 1987 as Fantastic Voyage II and " dealt not with competing submarines in the bloodstream, but with one submarine, with American hero cooperating ( not entirely voluntarily ) with four Soviet crew members ".
The novel was not made into a movie, however.

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