Page "General paresis of the insane" Paragraph 6

In her 1915 novel, The Song of the Lark, Willa Cather referred to the insanity of the wife of a main character as having been caused by general paresis but there is no hint that the character had contracted syphilis.

In her 1953 novel, A Pocket Full of Rye, Agatha Christie used paresis as an explanation for the behavior of the victim.

She did not mention the syphilitic connection.