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It was not until 1761, when he was in his eightieth year, that he brought out the great work which, once for all, made pathological anatomy a science, and diverted the course of medicine into new channels of exactness or precision — the De Sedibus et causis morborum per anatomem indagatis, which during the succeeding ten years, notwithstanding its bulk, was reprinted several times ( thrice in four years ) in its original Latin, and was translated into French ( 1765 ), English ( 1769 ), and German ( 1771 ).
Some account of this remarkable work remains now to be given.

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