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Golems seem to have some limited abilities to harm humans.
In Going Postal, Mister Pump ( AKA Pump Nineteen ) has had the rule " A Golem May Not Harm A Human Being Or Allow A Human Being To Come To Harm " amended to add " Except When Ordered To By Duly Constituted Authority.
" After his Chem is destroyed, Dorfl tells Dragon King Of Arms the Vampire that Dorfl could crush him, essentially killing him, but will not because it would be immoral to do so.
In Making Money, Adora Belle Dearheart tells Lord Vetinari that historically, cultures did not build Golems who could kill, and this implies that even modifying the Chem would not make a Golem able to kill.
Since the Umnian Golems had their Chem inscribed directly in their clay, and it could not be modified, perhaps most golems have the " cannot kill " stricture engraved directly in their clay before firing.
Dorfl could be an exception since the whole top of his head was sheared off in his fight with Meshugah, perhaps destroying any strictures which were " hard coded.

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