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Some incompatibilities exist because game software depends on certain peculiarities of the PS2 drive hardware.
Additional incompatibilities arise from the use of dual-layer DVDs in some PS2 games, which are sometimes not parsed properly by HD Loader ( incidentally, dual-layer games can only be installed from a PC but as of 0. 8c it's possible to install them from HD Loader ).
Finally, there are intentional impediments introduced some recent high-profile PS2 titles, such as God of War and Gran Turismo 4, to prevent them from being executed off the hard drive.
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