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Hatshepsut died as she was approaching what we would consider middle age given typical contemporary lifespans, in her twenty-second regnal year.
The precise date of Hatshepsut's death — and the time when Thutmose III became the next pharaoh of Egypt — is considered to be Year 22, II Peret day 10 of her reign, as recorded on a single stela erected at Armant or January 16, 1458 BC.
This information validates the basic reliability of Manetho's kinglist records since Hatshepsut's known accession date was I Shemu day 4, ( i. e.: Hatshepsut died 9 months into her 22nd year as king, as Manetho writes in his Epitome for a reign of 21 years and 9 months ).
If the recent identification of her mummy ( see below ) is correct, however, the medical evidence would indicate that she suffered from diabetes and died from bone cancer which had spread throughout her body while she was in her fifties.
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