Page "Hemoglobin" Paragraph 6

The oxygen-carrying protein hemoglobin was discovered by Hünefeld in 1840.

In 1851, Otto Funke published a series of articles in which he described growing hemoglobin crystals by successively diluting red blood cells with a solvent such as pure water, alcohol or ether, followed by slow evaporation of the solvent from the resulting protein solution.

Hemoglobin's reversible oxygenation was described a few years later by Felix Hoppe-Seyler.