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The virus persists in the liver in about 85 % of those infected.
This persistent infection can be treated with medication: the standard therapy is a combination of peginterferon and ribavirin, with either boceprevir or telaprevir added in some cases.
Overall, 50 – 80 % of people treated are cured.
Those who develop cirrhosis or liver cancer may require a liver transplant.
is the leading cause of liver transplantation, though the virus usually recurs after transplantation.
No vaccine against is available.

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