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* On the " Island Of Terror " ( 1966 ), silicon based life-forms are created accidentally by scientists while researching a cure for cancer.
The " Silicates " are not pretty, they feed on bones ( human or otherwise ) and they can reproduce by mitosis.
Not much to say about the scientific side though, since the survivors ignore how the creatures are exactly made of.
They eventually use a very 60's way to defeat them.

2.069 seconds.