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From a recent article: " The progressive course of s-IBM leads slowly to severe disability.
Finger functions can become very impaired, such as for manipulating pens, keys, buttons, and zippers, pulling handles, and firmly grasping handshakes.
Arising from a chair becomes difficult.
Walking becomes more precarious.
Sudden falls, sometimes resulting in major injury to the skull or other bones, can occur, even from walking on minimally-irregular ground or from other minor imbalances outside or in the home, due to weakness of quadriceps and gluteus muscles depriving the patient of automatic posture maintenance.
A foot-drop can increase the likelihood of tripping.
Dysphagia can occur, usually caused by upper esophageal constriction that often can be symptomatically improved, for several months to years, by bougie dilation per a GI or ENT physician.
Respiratory muscle weakness can sometimes eventuate.

1.983 seconds.