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When control of insulin levels fails, diabetes mellitus can result.
As a consequence, insulin is used medically to treat some forms of diabetes mellitus.
Patients with type 1 diabetes depend on external insulin ( most commonly injected subcutaneously ) for their survival because the hormone is no longer produced internally.
Patients with type 2 diabetes are often insulin resistant and, because of such resistance, may suffer from a " relative " insulin deficiency.
Some patients with type 2 diabetes may eventually require insulin if other medications fail to control blood glucose levels adequately.
Over 40 % of those with Type 2 diabetes require insulin as part of their diabetes management plan.

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