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In 2006, the ESSIC society proposed more rigorous and demanding diagnostic methods with specific classification criteria so that it cannot be confused with other, similar conditions.
Specifically, they require that a patient must have pain associated with the bladder, accompanied by one other urinary symptom.
Thus, a patient with just frequency or urgency would be excluded from a diagnosis.
Secondly, they strongly encourage the exclusion of confusable diseases through an extensive and expensive series of tests including ( A ) a medical history and physical exam, ( B ) a dipstick urinalysis, various urine cultures, and a serum PSA in men over 40, ( C ) flowmetry and post-void residual urine volume by ultrasound scanning and ( D ) cystoscopy.
A diagnosis of IC / BPS would be confirmed with a hydrodistention during cystoscopy with biopsy.

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