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In Bedford Falls, New York on Christmas Eve, George Bailey ( James Stewart ) is deeply troubled.
Prayers for his well-being from friends and family reach Heaven.
Clarence Odbody ( Henry Travers ), Angel Second Class, is assigned to save George and earn his wings.
Franklin and Joseph, the head angels, review George's life with Clarence.
At the age of 12, George ( Bobby Anderson ) saved his younger brother Harry ( George Nokes ), who had fallen through the ice on a frozen pond, though George lost the hearing in his left ear in this effort.
Later, working in the local pharmacy, George luckily noticed that druggist Mr. Gower ( H. B. Warner ), despondent over his son's death, had mistakenly filled a child's prescription with poison and saved the poor man from irrevocably ruining his own life by inadvertently killing the child.

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