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Her seminal works among laypeople are her memoir An Unquiet Mind, which details her experience with severe mania and depression, and Night Falls Fast: Understanding Suicide, providing historical, religious, and cultural responses to suicide, as well as the relationship between mental illness and suicide.
In Night Falls Fast, Jamison dedicates a chapter to American public policy and public opinion as it relates to suicide.
Her second memoir, Nothing Was the Same, examines her relationship with her second husband, the psychiatrist Richard Jed Wyatt, who was Chief of the Neuropsychiatry Branch

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