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Despite the law enforcement surveillance, Luciano was able to greatly expand narcotics trafficking to the United States by Cosa Nostra, making it one of organized crime's most lucrative ventures.
Between October 10 and October 14, 1957, Luciano oversaw a parley of more than thirty Sicilian and American Mafia leaders to draw up plans for the smuggling and distribution of heroin into the United States.
According to Selwyn Raab, an investigative reporter for The New York Times, it was at the Luciano meeting, held in the Grand Hotel et des Palmes in Palermo, Sicily, that a plan was put into place through which Sicilians were responsible for distributing heroin in the U. S., while the American mobsters collected a share of the income as " franchise fees ".
Luciano's plan included a scheme to expand the tiny heroin and cocaine market in the U. S. by reducing the price and focusing on working class white and black urban neighborhoods.

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