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James and Mary had two sons.
James Stewart, Duke of Rothesay, was born 22 May 1540 at St Andrews.
Robert was born and baptised on 12 April 1541, but both died on 21 April 1541, when James was nearly one year old and Robert was eight days old.
Mary's mother Antoinette de Bourbon wrote that the couple was still young and should hope for more children.
She thought a change of wet-nurse and over-feeding may not have helped.
The third and last child of the union was a daughter Mary, who was born on 8 December 1542.
King James died six days later, making the infant Mary queen regnant of Scotland.

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