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Maximus II was a 5th century patriarch of Antioch.

After the deposition of Domnus II by the Second Council of Ephesus, 449, Dioscorus persuaded the emperor Theodosius II to fill the vacancy with one of the clergy of Constantinople.

Maximus was selected and ordained, in violation of canon law, by Patriarch Anatolius of Constantinople, without the official sanction of the clergy or people of Antioch.