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According to Socrates Scholasticus he attended the synod of Seleucia in the autumn of 359, and then subscribed to the Acacian formula.
Early in 360 he became bishop of Antioch, succeeding Eudoxius, who had been translated to the see of Constantinople.
Early the following year, 361, he was in exile.
According to an old tradition, supported by evidence drawn from Epiphanius of Cyprus and John Chrysostom, this was due to a sermon preached before the emperor Constantius, in which he revealed Homousian views.
This explanation, however, is rejected by G. F. Loofs-the sermon contains nothing inconsistent with the Acacian position favoured by the court party ; on the other hand, there is evidence of conflicts with the clergy, quite apart from any questions of orthodoxy, which may have led to the bishop's deposition.

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