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The first report of CA-MRSA occurred in 1981, and in 1982 there was a large outbreak of CA-MRSA among intravenous drug users in Detroit, Michigan.
Additional outbreaks of CA-MRSA were reported through the 1980s and 1990s, including outbreaks among Australian Aboriginal populations that had never been exposed to hospitals.
In the mid 1990s there were scattered reports of CA-MRSA outbreaks among US children.
While HA-MRSA rates stabilized between 1998 – 2008, CA-MRSA rates continued to rise.
A report released by The University of Chicago Children's Hospital comparing two time periods ( 1993 – 1995 and 1995 – 1997 ) found a 25-fold increase in the rate of hospitalizations due to MRSA among children in the United States.
In 1999 The University of Chicago reported the first deaths from invasive MRSA among otherwise healthy children in the United States.
By 2004 MRSA accounted for 64 % of hospital-acquired S. aureus infections in the United States.

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