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Historically, mushrooms have long been thought to hold medicinal value, especially in traditional Chinese medicine.
They have been studied in modern medical research since the 1960s, where most studies use extracts, rather than whole mushrooms.
Only a few specific extracts have been tested for efficacy in laboratory research.
Polysaccharide-K and lentinan are among extracts best understood from in vitro research, animal models such as mice, or early-stage human pilot studies.

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