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In the 1930s the decision was made to move the Institute to new premises.
An imposing copper-roofed building at Mill Hill was designed by Maxwell Ayrton, also the architect of the original Wembley Stadium, and construction began in 1937.
Once again, occupation was delayed when war broke out in 1939 and the building was given to the Women's Royal Naval Service.
The building was returned to the MRC in autumn 1949 but Sir Henry Dale had retired in 1942 and so was never director on the new site, that job falling to his successor Sir Charles Harington.

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