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Due to the relative frequency of infection and the emerging development of antibiotic resistance in strains of N. gonorrhoeae, vaccines are thought to be an important goal in the prevention of infection.
However, there have been a relatively low emphasis on research to such a vaccine in the medical literature and few human clinical trials for prospective vaccines.
The ability to develop an effective vaccine has been limited by the lack of acquired immunity to infection to model a vaccine after and the current lack of commitment in effort and resources.

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