Page "Nerve" Paragraph 13

Within the endoneurium, the individual nerve fibers are surrounded by a low protein liquid called endoneurial fluid.

The endoneurium has properties analogous to the blood – brain barrier, in that it prevents certain molecules from crossing from the blood into the endoneurial fluid.

In this respect, endoneurial fluid is similar to cerebro-spinal fluid in the central nervous system.

During the development of nerve edema from nerve irritation or ( injury ), the amount of endoneurial fluid may increase at the site of irritation.

This increase in fluid can be visualized using magnetic resonance neurography, and thus MR neurography can identify nerve irritation and / or injury.