Page "Neurotransmitter receptor" Paragraph 3

There are two types of Neurotransmitter receptors: ligand-gated receptors or ionotropic receptors and G protein-coupled receptors or metabotropic receptors.

Ligand-gated receptors can be excited by neurotransmitters ( ligands ) like glutamate and aspartate.

These receptors can also be inhibited by neurotransmitters like GABA and glycine.

Conversely, G protein-coupled receptors are neither excitatory nor inhibitory.

Rather, they modulate the actions of excititory and inhibitory neurotransmitters.

Most neurotransmitters receptors are G-protein coupled.