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Pre-Columbian inhabitants of eastern North America considered the Ohio part of a single river continuing on through the lower Mississippi.
The river's name comes from the Seneca ( Iroquoian ) ohiːyo, a proper name derived from ohiːyoːh, meaning " good river ".
The river is long and carries the largest volume of water of any tributary of the Mississippi.
The Indians and early explorers and settlers of the region also often considered the Allegheny to be part of the Ohio.
The forks ( the confluence of the Allegheny and Monongahela rivers at what is now Pittsburgh ) was considered a strategic military location.

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