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Although initial treatment of the disease usually involves injections of B < sub > 12 </ sub > to rapidly replace body stores, a number of studies have shown long-term vitamin replacement treatment may be maintained with high-dose oral B < sub > 12 </ sub > supplements, since sufficient B < sub > 12 </ sub > is absorbed from these by a normal intestine, even without any intrinsic factor.
In this regard, nasal and sublingual forms of B < sub > 12 </ sub > have not been found to have any special value over simple swallowed tablets.

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