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In 1964, she appeared in two medical dramas — as Alicia Carter in The Eleventh Hour episode " My Door Is Locked and Bolted ", and as Alice Marin in the Breaking Point episode " The Summer House ".
In 1990-91, she starred as the devious Catherine Martell in David Lynch's television series Twin Peaks.
She appeared in Other People's Money with Gregory Peck ( 1991 ), and in horror maestro Dario Argento's first American film Trauma ( 1993 ).
She played George Clooney's character's mother on ER.
In 1998, she appeared in the sci-fi thriller The Faculty.
She made guest appearances on television shows such as Frasier, Matlock, State of Grace, Will & Grace, Cold Case, and Law & Order: Special Victims Unit.
She returned to the big screen for independent films such as Eulogy and The Dead Girl.

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