Page "Short-term memory" Paragraph 11
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Various researchers have proposed that stimuli are coded in short-term memory using transmitter depletion.
According to this hypothesis, a stimulus activates a spatial pattern of activity across neurons in a brain region.
As these neurons fire, the available neurotransmitters in their store are depleted and this pattern of depletion is iconic, represents stimulus information and functions as a memory trace.
The memory trace decays over time as a consequence of neurotransmitter reuptake mechanisms that restore neurotransmitters to the levels that existed prior to stimulus presentation.
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