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Sofonisba Anguissola ( also spelled Anguisciola ) ( c. 1532 – 16 November 1625 ) was an Italian Renaissance painter born in Cremona.

She received a well-rounded education that included the fine arts and her apprenticeship with local painters set a precedent for women to be accepted as students of art.

Anguissola traveled to Rome, where she was introduced to Michelangelo who immediately recognized her talent, Milan, where she painted the Duke of Alba, Madrid, which was a turning point in her career serving as a court painter and painting many official portraits for the Spanish court, and Palermo, Pisa, and Genoa, where she was the leading portrait painter.