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Approaching the egg cell is a rather complex, multistep process of chemotaxis guided by different chemical substances / stimuli on individual levels of phylogeny.
One of the most significant, common signaling character of the event is that a prototype of professional chemotaxis receptors, formyl peptide receptor ( 60. 000 receptor / cell ) as well as the activator ability of its ligand formyl Met-Leu-Phe have been demonstrated in the surface membrane even in the case of human sperms.

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