Page "Typhoid fever" Paragraph 45

Most developed countries saw declining rates of typhoid fever throughout the first half of the 20th century due to vaccinations and advances in public sanitation and hygiene.

In 1908, the chlorination of drinking water was a significant step in the control of typhoid fever in the U. S. The first permanent disinfection of drinking water in the U. S. occurred on the Jersey City, New Jersey water supply.

Credit for the decision to build the chlorination system has been given to John L. Leal The chlorination facility was designed by George W. Fuller.

Antibiotics were introduced in clinical practice in 1942, greatly reducing mortality.

Today, the incidence of typhoid fever in developed countries is around 5 cases per 1, 000, 000 people per year.